What Foods Should I Eat When Taking Levodopa/Carbidopa?

​If you or a loved one is living with Parkinson’s disease and taking Levodopa/Carbidopa, you may have noticed that your meals can impact how well your medication works. While this medication is one of the most effective treatments for managing motor symptoms, the foods you eat—and when you eat them—can affect how it’s absorbed in your body. The good news? With a few simple dietary strategies, you can make the most of your treatment and feel more in control. 

This post is for general information only and not medical advice. Always consult your doctor about your health and treatment decisions.

Timing Is Everything
Levodopa/Carbidopa works best when taken on an empty stomach. That’s because protein-rich foods (like meat, eggs, dairy, and legumes) can compete with the medication for absorption in the small intestine. This competition can lead to a delayed or reduced effect of the medication, making symptoms more difficult to manage.

To avoid this, many people find it helpful to take Levodopa/Carbidopa 30 to 60 minutes before meals, or at least 1 to 2 hours after eating. Always follow your doctor’s specific instructions, but being mindful of timing can dramatically improve symptom control.

Protein: Balance, Don’t Eliminate
You still need protein—it’s essential for muscle strength and overall health. Instead of cutting it out completely, consider spreading your protein intake throughout the day or reserving it for the evening, when medication timing may be less critical. This approach is often called a protein redistribution diet, and your healthcare team or dietitian can help tailor it to your needs.

Nutrients That Support Parkinson’s Health
In addition to adjusting protein intake, focus on nutrient-dense foods that support brain and body function:

• Fruits and vegetables: Rich in antioxidants that may reduce oxidative stress.
• Whole grains: Provide fiber to help manage constipation—a common PD symptom.
• Healthy fats: From sources like olive oil, nuts, and avocados, which support brain health.
• Fluids: Staying hydrated helps medications work effectively and combats common symptoms like low blood pressure.

Foods to Watch

• High-protein meals at medication times: May interfere with Levodopa absorption.
• Iron supplements: These can also interfere with medication—take them at a different time if needed.
• Sugary or processed foods: These offer little nutritional value and may contribute to energy dips.

Why Support Matters
A diagnosis of any form of Parkinson’s can feel overwhelming. But with the right support and resources, individuals can maintain independence, quality of life, and emotional well-being.
For resources, referrals, and support in navigating Parkinson’s and related conditions, contact the Parkinson’s Association of Southwest Florida at www.paswfl.org or call 239-417-3465.

For over 25 years, PASWFL has provided free, high-quality services and programs to individuals and families affected by Parkinson’s disease in Southwest Florida.
Each week, PASWFL offers more than 25 free programs and support groups, including:

• Wellness and fitness classes
• Speech and cognitive therapy
• Educational seminars
• Support for care partners
• Support groups

There are no fees to become a member, and PASWFL welcomes anyone touched by PD.

Take the First Step Toward Living Well
If you suspect early Parkinson’s or have been recently diagnosed, you don’t have to face it alone.
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