The Effects of Intermittent Fasting on Brain and Cognitive Function Gudden J, Arias Vasquez A, Bloemendaal M. The Effects of Intermittent Fasting on Brain and Cognitive Function. Nutrients. 2021; 13(9):3166. https://doi.org/10.3390/nu13093166
Intermittent fasting (IF) — a pattern of restricting eating to a set interval — is now a well-studied approach to signaling the body to switch from getting its fuel from glucose stored in the liver to ketones that are stored in fat. The benefits to your body from that energy source switch is that ketones released in the blood during fasting signal molecules that initiate activity in certain cellular signaling pathways. The activation has been shown to influence the body’s defenses against oxidative and metabolic stress and to remove or repair damaged molecules. The practice has gained popularity for both its ability to help manage weight, blood sugar levels and overall health.
Recent animal studies include measuring the effects of IF on brain and cognitive function as related to neurological disorders including Parkinson’s Disease. Using mice manipulated to show PD-like behavior showed greater retention of motor skills and less dopaminergic neuronal loss than the control mice. Clinical trials on persons with PD require additional time to assess the disease-modifying effects of IF. CLICK TO READ THE FULL PAPER
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