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  • Home
    • Hurricane Resources
  • Living Well with PD
    • Living Well with PD Parksinsons Awareness
    • PD 101 Free Sign Up Learn More
    • Start Here for the Newly Diagnosed
    • Community Resources >
      • Community Support Initiatives
      • Movement Disorder Specialists and Neurologists
      • Additional Classes in SWFL for PD
      • Additional SWFL resources for PD
    • Participate in a PD Study
    • Articles & Research on PD >
      • GOLF COURSE PROXIMITY AND INCREASED RISK FOR PD
      • Social Support Improves PD Symptoms
      • Exercise Improves PD Outcomes
      • Genetic Role in PD
      • Advances in PD
      • Genetic Link to PD
      • Exercise and improved executive Functioning with PD
      • Exercise and Fall Prevention with PD
      • Intimacy and PD
      • spinal cord neuroprosthesis and PD
      • Advance Care Planning and PD
      • Cognitive Impairment Treatment PD
      • Mercury and PD
      • Cognitive Remediation Therapy
      • COVID Vulnerability and PD
      • Postural Instability Severity PD
      • Early Trial for Treatment Shows Promise
      • Biomarker Found
      • Therapeutic Benefits of Dance
      • Ultrasound Therapy for PD
      • Improvisational Theatre for PD
      • PD Detection using AI and Breathing Patterns
      • ALTERNATIVE MOVEMENT EXERCISE
      • NON INVASIVE TREATMENT R-TMS
      • Group Therapy
      • Multidisciplinary Approach to PD
      • VIBRATING GLOVE SHOWES PROMISE
      • Prevalence of PD Underestimated
      • Differences in Men and Women with PD
      • Intermittent Fasting for PD
      • Meditation and Complementary Therapy for PD
      • Cognitive Impairment and PD
      • Aerobic Exercise Alters Brain Function in PD
      • A-Synuclein Biomarker
      • Mediterranean Diet for PD
      • Regular Exercise Improve PD Quality of Life
    • Videos of PD Talks
    • Info about PD >
      • Parkinson Disease in Florida
      • 10 things to know about PD
      • More About PD
  • Members Only
  • Programs & Events
    • Sample Calendar of Activities
    • Movement Classes
    • Support Groups
    • Speech & Music
    • Just for Fun Wellness Classes
    • Education Programs
    • Caregiver Programs
    • EARLY ONSET PD
    • Lunch Bunch
    • Events >
      • Bingo for Bags and Baubles
      • Mingle & Share a PD Resource Fair
      • Step Up for PD Walk
      • A Step Forward Overcoming Obstacles Luncheon
      • Education Symposium
  • About Us
    • Our Mission
    • Board of Directors
    • Staff
    • News/Press >
      • 2023-24 Board Announced
    • Blog
  • Become a Member
    • Complete a Participation Waiver
  • GET INVOLVED
    • PD 101 Free Sign Up
    • ENEWS SIGN UP
    • Contact us
  • DONATE
    • PARKINSONS AWARENESS MONTH GIVING
    • Our Giving Society
    • ANNUAL FUND
    • IN HONOR
    • IN MEMORY
    • Planned Giving

Parkinson's Association 
SWFL Blog

All blog posts are for general information only and not medical advice. Always consult your doctor about your health and treatment decisions.

What is Off-Time with Parkinson’s?

8/9/2025

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If you or a loved one has Parkinson’s disease (PD), you may have heard the term “off-time”—but what does it really mean? Imagine you’ve taken your medication and felt your symptoms improve. Your movements are smoother, your tremors less noticeable, and you can do the things you enjoy. Then, often unexpectedly, those benefits wear off, and your symptoms return before your next scheduled dose. That period when your medication is not working as well as it should? That’s off-time—and for many people with Parkinson’s, it can be one of the most challenging parts of living with the condition.
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Understanding Off-Time
Parkinson’s is caused by the loss of dopamine-producing brain cells. While medications like levodopa help replace or mimic dopamine, they can only do so for a limited period before wearing off. Off-time occurs when the effects fade, often bringing back stiffness, slowness, tremors, or difficulty walking. Some people experience non-motor symptoms as well, such as anxiety, fatigue, or mood changes.

Off-time can be predictable—happening at specific intervals between doses--or unpredictable, appearing suddenly without warning. As Parkinson’s progresses, off-time can become more frequent and harder to manage, significantly impacting independence and quality of life.
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Managing Off-Time
The good news is that there are strategies to reduce off-time and help people live more comfortably. These may include:
  • Medication adjustments: Changing dosage timing or using longer-acting forms.
  • Add-on therapies: Medications that extend the effect of levodopa.
  • Lifestyle approaches: Exercise, stress management, and balanced nutrition can help.
  • Advanced treatments: For some, deep brain stimulation or continuous infusion therapies may be options.
If you notice symptoms returning before your next dose, track the timing, severity, and triggers. Share this information with your neurologist or movement disorder specialist—they can help tailor your treatment plan to manage off-time better.
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Why Support Matters
A diagnosis of any form of Parkinson’s can feel overwhelming. But with the right support and resources, individuals can maintain independence, quality of life, and emotional well-being.
For resources, referrals, and support in navigating Parkinson’s and related conditions, contact the Parkinson’s Association of Southwest Florida at www.paswfl.org or call 239-417-3465.

For more than 25 years, PASWFL has provided free, high-quality services and programs to individuals and families affected by Parkinson’s disease in Southwest Florida. Their goal is simple: help people live well with PD, regardless of where they are in their journey.

Each week, PASWFL offers more than 25 free programs and support groups, including:
  • Wellness and fitness classes
  • Speech and cognitive therapy
  • Educational seminars
  • Support for care partners
  • Support groups
There are no fees to become a member, and PASWFL welcomes anyone touched by PD.

Take the First Step Toward Living Well
If you suspect early Parkinson’s or have been recently diagnosed, you don’t have to face it alone.
👉 Click here to sign up for the PASWFL newsletter
👉 Click here to become a member (it’s free!)

Visit www.paswfl.org and discover the power of support, education, and community.
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Parkinson's Association of Southwest Florida 
2575 Northbrooke Plaza Drive
Suite#301, Naples, FL 34119
239-417-3465

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