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If you or a loved one has Parkinson’s disease (PD), you may have heard the term “off-time”—but what does it really mean? Imagine you’ve taken your medication and felt your symptoms improve. Your movements are smoother, your tremors less noticeable, and you can do the things you enjoy. Then, often unexpectedly, those benefits wear off, and your symptoms return before your next scheduled dose. That period when your medication is not working as well as it should? That’s off-time—and for many people with Parkinson’s, it can be one of the most challenging parts of living with the condition. Understanding Off-Time Parkinson’s is caused by the loss of dopamine-producing brain cells. While medications like levodopa help replace or mimic dopamine, they can only do so for a limited period before wearing off. Off-time occurs when the effects fade, often bringing back stiffness, slowness, tremors, or difficulty walking. Some people experience non-motor symptoms as well, such as anxiety, fatigue, or mood changes. Off-time can be predictable—happening at specific intervals between doses--or unpredictable, appearing suddenly without warning. As Parkinson’s progresses, off-time can become more frequent and harder to manage, significantly impacting independence and quality of life. Managing Off-Time The good news is that there are strategies to reduce off-time and help people live more comfortably. These may include:
Why Support Matters
A diagnosis of any form of Parkinson’s can feel overwhelming. But with the right support and resources, individuals can maintain independence, quality of life, and emotional well-being. For resources, referrals, and support in navigating Parkinson’s and related conditions, contact the Parkinson’s Association of Southwest Florida at www.paswfl.org or call 239-417-3465. For more than 25 years, PASWFL has provided free, high-quality services and programs to individuals and families affected by Parkinson’s disease in Southwest Florida. Their goal is simple: help people live well with PD, regardless of where they are in their journey. Each week, PASWFL offers more than 25 free programs and support groups, including:
Take the First Step Toward Living Well If you suspect early Parkinson’s or have been recently diagnosed, you don’t have to face it alone. 👉 Click here to sign up for the PASWFL newsletter 👉 Click here to become a member (it’s free!) Visit www.paswfl.org and discover the power of support, education, and community.
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