What Foods Should I Eat When Taking Levodopa/Carbidopa?

Levodopa/Carbidopa is one of the most effective medications used to manage the symptoms of Parkinson’s disease (PD). If you or a loved one is taking this medication, you may have wondered: What foods should I eat when taking Levodopa/Carbidopa? Nutrition plays a key role in how well the medication works and how you feel throughout the day.

How Food Affects Levodopa/Carbidopa Absorption

Levodopa must cross the blood-brain barrier to be effective, and protein can interfere with this process. This is because the body uses the same transport system for both Levodopa and amino acids (the building blocks of protein). As a result, if you eat a high-protein meal around the same time you take your medication, it may compete with Levodopa and reduce its effectiveness.

That doesn't mean you should avoid protein altogether—your body still needs it to stay strong. Instead, timing and balance are key.

Best Practices for Eating While Taking Levodopa/Carbidopa 

1. Take Your Medication on an Empty Stomach
For many people, Levodopa/Carbidopa is best absorbed when taken 30 to 60 minutes before meals. This helps prevent protein interference and can improve the medication’s effectiveness.

2. Schedule Protein Wisely
Try to limit protein intake during the day and consume the majority of your protein in the evening when symptoms tend to be less problematic. This approach can help ensure your medication works better when you need it most—during your active hours.

3. Stay Hydrated
Water helps with digestion and medication absorption. Make sure to drink plenty of fluids throughout the day, unless otherwise directed by your physician.

4. Focus on Fiber-Rich Foods
Constipation is common in Parkinson’s disease and can worsen symptoms. Eating foods high in fiber such as whole grains, fruits, and vegetables can promote regular bowel movements and improve overall well-being.

5. Avoid High-Fat, High-Sugar Meals
Fatty and sugary foods can slow digestion and may contribute to inflammation. Opt for nutrient-dense foods like leafy greens, berries, nuts, and lean proteins.

Partnering with the Parkinson’s Association of Southwest Florida

Living well with Parkinson’s involves more than medication—it requires comprehensive support, including guidance on nutrition, exercise, and lifestyle. That’s where the Parkinson’s Association of Southwest Florida (PASWFL) comes in.

For over 25 years, PASWFL has provided free programs, expert education, and compassionate support to individuals and families living with Parkinson’s disease and related neurological conditions in our community.

Each week, they offer more than 25 programs and support groups for individuals with PD and their care partners. These include nutrition counseling, fitness classes, education events, and support circles—all designed to help you thrive.

Best of all, membership is free and open to everyone in Southwest Florida.

Get Connected
Click here to sign up for PASWFL’s free newsletter
Click here to become a free member today
To learn more, visit www.parkinsonassociationswfl.org and take the next step toward living well with Parkinson’s disease.