What Is the New Drug for Parkinson’s?

In recent years, several new drugs have gained attention for their ability to manage Parkinson’s symptoms more effectively or to address underlying causes of the disease. One of the newest FDA-approved drugs is istradefylline (Nourianz), a novel add-on treatment that targets the brain’s adenosine A2A receptors. It's used in combination with levodopa/carbidopa to help reduce “off” episodes — times when medication effects wear off and symptoms return.

Another noteworthy development is opicapone (Ongentys), a once-daily COMT (catechol-O-methyltransferase) inhibitor that also reduces “off” time in people taking levodopa. Its convenient dosing and favorable side effect profile make it a useful option for many patients.

On the cutting edge, gene therapy and disease-modifying treatments are in clinical trials. These therapies aim not just to relieve symptoms but to slow or halt the progression of Parkinson’s at the cellular level. For example, PT320, a sustained-release formulation of exenatide, is under investigation for its potential neuroprotective effects.

Although these new drugs and therapies represent exciting progress, it’s important to remember that treatment must be personalized. What works well for one person may not work for another, so it’s essential to work closely with a neurologist or movement disorder specialist to tailor a care plan.

Beyond Medication: Support Is Essential
New drug therapies can improve daily life, but medication alone isn’t enough. People with Parkinson’s disease need access to education, community support, and wellness programs. That’s where the Parkinson’s Association of Southwest Florida (PASWFL) plays a vital role.

For over twenty-five years, PASWFL has provided free programs and services that improve the quality of life, educate, enrich, and empower Southwest Floridians touched by PD and related neurological diseases. Each week, the organization offers more than 25 free programs and support groups for people living with Parkinson’s and their care partners. These include exercise classes, speech therapy, wellness education, and much more.

Membership  is completely free, and applying is easy via our website at www.parkinsonassociationswfl.org.

• Click here to sign up for the PASWFL newsletter and stay informed about the latest in Parkinson’s treatment, research, and local events.
• Click here to become a PASWFL member for free and access valuable resources and support.

Staying informed and connected can make all the difference. As the search for a cure continues, organizations like PASWFL remain a cornerstone of hope and strength for those facing Parkinson’s disease.