What Is the Number One Treatment for Parkinson’s Disease?

One of the most common questions after a Parkinson’s disease (PD) diagnosis is: What is the number one treatment for Parkinson’s disease?
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The answer is not as simple as naming a single pill or procedure. Parkinson’s is a complex neurological condition, and the most effective treatment approach is one that is personalized, progressive, and supported over time.
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Here’s the key truth: while medication is essential, the most effective “treatment” for Parkinson’s disease is a comprehensive care approach that combines medical therapy, movement, education, and ongoing support. Keep reading to learn more.

​1. What Most People Are Never Told:
Many people are surprised to learn that medication alone is not enough to manage Parkinson’s disease long-term. Research consistently shows that people with PD who combine medical treatment with exercise, therapy, education, and support experience better mobility, improved mood, and a higher quality of life than those who rely on medication alone.

2. The Foundation: Medication for Parkinson’s Disease
​From a medical standpoint, carbidopa/levodopa is widely considered the gold standard and most effective medication for treating Parkinson’s motor symptoms. It works by replenishing dopamine in the brain, helping improve:

• Slowness of movement (bradykinesia)
• Muscle rigidity
• Tremor
• Walking and balance challenges

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Other medications — such as dopamine agonists, MAO-B inhibitors, and COMT inhibitors — may be used alone or in combination, depending on symptoms and disease stage. Advanced treatments like Deep Brain Stimulation (DBS) or infusion therapies may be appropriate for some individuals.
However, medication treats symptoms — it does not stop disease progression.

3. ​The Number One Treatment:
A Comprehensive, Team-Based ApproachThe most effective treatment for Parkinson’s disease is a multidisciplinary care model that includes:

• Neurologist or movement disorder specialist
• Physical exercise and wellness programs
• Speech and voice therapy
• Education about Parkinson’s and symptom management
• Emotional and social support

Exercise, in particular, is one of the most powerful non-drug treatments for Parkinson’s. Regular, targeted movement has been shown to:

• Improve balance and mobility
• Slow functional decline
• Reduce stiffness
• Support cognitive and emotional health

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Just as important is support — having access to trusted information, peer connections, and care partner resources.

4. Why Support Matters:
A diagnosis of any form of Parkinson’s can feel overwhelming. But with the right support and resources, individuals can maintain independence, quality of life, and emotional well-being.

For resources, referrals, and support in navigating Parkinson’s and related conditions, contact the Parkinson’s Association of Southwest Florida (PASWFL) at www.paswfl.org or call 239-417-3465.
For over 25 years, PASWFL has provided free, high-quality services and programs to individuals and families touched by Parkinson’s disease in Southwest Florida. Their goal is simple: help people live well with PD, regardless of where they are in their journey.

Each week, PASWFL offers more than 25 free programs and support groups, including:

• Wellness and fitness classes
• Speech Exercise classes
• Educational seminars
• Support for care partners
• Support groups

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There are no fees to become a member, and PASWFL welcomes anyone touched by PD.

​Take the First Step Toward Living WellIf you suspect early Parkinson’s or have been recently diagnosed, you don’t have to face it alone.
👉 Sign up for the PASWFL newsletter: https://parkinsonassociationswfl.org/signup-enews.html
👉 Become a member — it’s free and confidential: https://parkinsonassociationswfl.org/signup.html
To learn more, visit www.paswfl.org and discover the power of support, education, and community.